Progesterone, ovulation & fertility

Posted by on Mar 28, 2012 in Fertility, Hormone Balance | 2 comments

A reader writes:

My nurse-midwife recently told me that the progesterone cream could be causing me not to ovulate. Have you heard of this before? She suggested I stop using it for a few months and then see if we get pregnant. We haven’t officially started trying every month, but we haven’t used any preventative measures, so I was surprised we hadn’t gotten pregnant yet. What are your thoughts?

If used every single day without any breaks, the progesterone cream could cause a “rest state” for ovaries. That’s why we have women who don’t have regular periods or who have PCOS use progesterone for 90 days straight. It’s when we stop the progesterone, after those 90 days, that they ovulate and then usually get pregnant in month 4. But if you are using it the back half of your cycle, you should be ovulating.


  1. I am looking for information for my sister who is currently not ovulating, and does not get her period. She has one child and is looking to get pregnant again. She isn’t currently taking anything, and has Prolief cream, but doesn’t know when to start it and how long to take it.?? Any advice would be great! She tried a couple options including a pill from the Dr and it made her feel extremely irritable and worse!
    Thanks for your time:)

    • Your sister would benefit from reading the Healing Handbook to gain a greater understanding of overall hormone balance. Here is an excerpt from Dr. Deanna’s Healing Handbook that will explain how to use Prolief for someone who is not ovulating:

      Bioidentical progesterone can be used for female infertility, when the issue is anovulation or no ovulation. Progesterone is a widely accepted treatment for anovulation among fertility specialists. Generally, if a woman is not ovulating, it is because she has low progesterone levels. She may or may not have a period.
      It is best to start out by using 20-40mg of USP Progesterone daily for 90 days, if you are not having a period. After the 90 days, stop using the progesterone and wait for a period. Once your period starts, begin using the progesterone on day 12 (of an average 28-day cycle) (at ovulation) through the start of your menstrual cycle. While most women do not have a 28-day cycle, I continue to use the 28-day cycle as a model in this book. The following guidelines are based on the average 28-day cycle and, again, may need adjusting for your particular cycle length.

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